- March 18
- Maurice "Rocket" Richard becomes the first NHL player to score 50 goals. [1]
- March 26
- De Paul wins NIT basketball championship, George Mikan scores 34. [1]
- March 27
- 7th NCAA Men's Basketball Championship: Oklahoma State beats NYU 49-44. [1]
- DePaul beats Bowling Green for NIT title. [1]
- April 9
- NFL requires players to wear long stockings. [1]
- April 10
- NFL's Boston Yankees and Brooklyn Tigers merge. [1]
- April 19
- 49th Boston Marathon won by John A Kelley of Massachusetts in 2:30:40.2. [1]
- April 20
- Cleveland Browns' organization formed by Arthur "Mickey" McBride. [1]
- April 22
- NHL Stanley Cup: Toronto Maple Leafs beat Detroit Red Wings, 4 games to 3. [1]
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- April 24
- Albert B "Happy" Chandler is named second baseball commissioner. [1]
- May 7
- Branch Rickey announces formation of the US Negro Baseball League. [1]
- May 9
- New balata ball used in baseball, 50 percent livilier. [1]
- May 18
- Detroit Tigers and Philadelphia Athletics both have seven straight games postponed due to rain. [1]
- May 19
- Start of the first Victory Test Cricket between England and Australia Services. [1]
- May 20
- Keith Miller scores 105 in the first Victory Test Cricket at Lord's. [1]
- May 21
- Australia Services win first Victory Test Cricket at Lord's by six wickets. [1]
- July 6
- Washington Senators' Rick Ferrell catches for a record 1,722 games. [1]
- July 21
- Detroit Tigers and Philadelphia Athletics play 24 innings 1-1 tie. [1]
- August 4
- Golfer Byron Nelson records most tournament wins (18) in a season. [1]
- Boston Red Sox player Tom McBride is third to get six RBIs in an inning (4th). [1]
- August 20
- Brooklyn Dodgers' Tommy Brown becomes youngest home run hitter (age 17). [1]
- September 1
- Philadelphia Phillies' Vince DiMaggio ties National League record with fourth grand slam of season. [1]
- September 9
- Jimmie Foxx hits his 534th and final home run. [1]
- Philadelphia Athletics' Dick Fowler no-hits Saint Louis Browns, 1-0. [1]
- September 22
- Stan Musial gets five hits off five pitchers on five consecutive pitches. [1]
- September 30
- Hank Greenberg's final day home run wins the pennant for the Detroit Tigers. [1]
- October 10
- Detroit Tigers beat Chicago Cubs, 4 games to 3 in 42nd World Series. [1]
- October 14
- Chicago Cardinals end a record 29-game losing streak, beat Chicago Bears. [1]
- November 10
- College football's #1 Army beats #2 Notre Dame 48-0. [1]
- November 22
- Jim Benton, Cleveland Rams' end, gains 303 yards (NFL record). [1]
- December 1
- Canadian Football League Grey Cup: Toronto Argonauts beat Winnipeg Blue Bombers, 35-0 at Toronto, Ontario. [1]
- December 4
- 11th Heisman Trophy Award: Doc Blanchard, Army (FB); he is first junior to win the trophy. [1]
- December 10
- Australian Services lose third Victory Test Cricket to India by six wickets. [1]
- December 16
- Cleveland Rams win NFL championship. [1]
- December 31
- Donald Bradman scores 112, his first post-War century, South Africa versus Australia Services. [1]
1946
- January 11
- Bert Bell becomes second NFL commissioner, moves Chicago, Illinois, headquarters to Philadelphia, Pennsylvania. [1]
- January 12
- NFL champions Cleveland Rams given permission to move to Los Angeles. [1]
- February 19
- New York Giants' outfielder Danny Gardella is first major league player to announce he is jumping to the "outlaw" Mexican League. [1]
- March 3
- US Ladies Figure Skating Championship won by Gretchen Merrill. [1]
- US Men's Figure Skating Championship won by Richard Button. [1]
- March 9
- Ted Williams is offered US$500,000 to play in Mexican League, he refuses. [1]
- March 23
- 8th NCAA Men's Basketball Championship: Oklahoma State beats North Carolina 43-40. [1]
- March 29
- First Test Cricket between Australia and New Zealand. [1]
- Test Cricket debuts of Lindwall, Miller and Tallon. [1]
- March 30
- Australia beats New Zealand in cricket at 3:30pm on second day. [1]
- Last Test Cricket appearance of Bill O'Reilly (5-14 and 3-19). [1]
- April 7
- 10th Golf Masters Championship: Herman Keiser wins, shooting a 282. [1]
- April 9
- NHL Stanley Cup: Montreal Canadiens beat Boston Bruins, 4 games to 1. [1]
- April 13
- Eddie Klepp, a white pitcher signed by defending Negro League champion Cleveland Buckeyes, is barred from field in Birmingham, Alabama. [1]
- April 14
- Manager Mel Ott of New York Giants hits 511th and final homerun. [1]
- April 18
- Jackie Robinson debuts as second baseman for the Montreal Royals. [1]
- April 19
- New York Yankees switch from third base to first base dug out. [1]
- April 20
- First televised baseball broadcast in Chicago, Illinois, Saint Louis Cardinals versus Chicago Cubs. [1]
- 50th Boston Marathon won by Stylianos Kyriakides of Greece in 2:29:27. [1]
- April 23
- Brooklyn Dodgers' Ed Head no-hits Boston Braves, 5-0. [1]
- April 24
- Eleven players (Tinker, Evers, Chance, Burkett, McCarthy, Waddell, Plank, Walsh, Chesbro, Griffith, and McGinnity) are named to Major League Baseball's Hall of Fame. [1]
- April 30
- Cleveland Indians' Bob Feller's second no-hitter beats New York Yankees, 1-0. [1]
- May 4
- 72nd Kentucky Derby: Warren Mehrtens aboard Assault wins in 2:06.6. [1]
- Washington Senators' Cecil Travis gets six straight hits before being stopped. [1]
- May 8
- Boston Red Sox' player Johnny Pesky scores six runs in one game. [1]
- May 10
- Boston Red Sox win 15th straight, beating New York Yankees 5-4, Joe DiMaggio hits Grand Slam. [1]
- May 11
- First night game at Boston Braves Field (New York Giants 5, Boston Braves 1). [1]
- 72nd Preakness: Warren Mehrtens aboard Assault wins in 2:01.4. [1]
- May 13
- Sarwate and Banerjee add 249 for 10th wicket for Indians versus Surrey. [1]
- May 20
- Chicago Cubs' Claude Passeau makes his first error since September 21, 1941, ending pitcher's fielding record of 273 consecutive errorless chances. [1]
- May 22
- New York Yankees turn triple-play and defeat Detroit Tigers' 5-3. [1]
- May 24
- Bill Dickey replaces Joe McCarthy as New York Yankees' manager. [1]
- May 26
- 2-for-42 and hitting .048 for 1946, Mel Ott stops playing baseball. [1]
- May 28
- First night game at Yankee Stadium (Washington Senators 2, New York Yankees 1). [1]
- May 30
- Boston Braves' Bernard Malamud's homerun shatters Bulova clock in Ebbets Field. [1]
- June 1
- Assault wins Belmont Stakes and Triple Crown. [1]
- June 6
- The 11 Basketball of America Association teams meet to schedule first season. [1]
- June 9
- 66,545 fans help New York Yankees break million attendance mark. [1]
- New York Giants' Mel Ott becomes the first manager to be ejected from both games of a doubleheader. [1]
- June 16
- Lloyd Mangrum wins golf's US open after two playoffs. [1]
- June 19
- First TV sports spectacular-Joe Louis versus Billy Conn. [1]
- July 12
- Vance Dinges hits the only Philadelphia Phillies' pinch hit inside-the-park home run. [1]
- July 14
- Cleveland Indians' Lou Boudreau hits four doubles and home run but Boston Red Sox win 11-10 on Ted Williams' 3 homeruns with 8 RBIs. [1]
- July 27
- Boston Red Sox player Rudy York hits two grand slams in one game. [1]
- August 9
- First time all major-league baseball games (8) are played at night. [1]
- August 18
- Golf Writers Associaton of America formed. [1]
- August 25
- Ben Hogan wins the PGA championship. [1]
- September 1
- Batty Berg wins the US Open. [1]
- September 2
- Johnny Neun replaces Bill Dickey as New York Yankees' manager. [1]
- September 6
- All-American Football Conference plays first game (Cleveland Browns 44, Miami Seahawks 0). [1]
- September 8
- San Francisco 49ers play first AAFC game, lose to New York Yankees 21-7. [1]
- September 15
- Brooklyn Dodgers beat Chicago Cubs 2-0 in five innings, games called because of gnats. [1]
- September 29
- First time National League pennant ends in a tie (Saint Louis Cardinals and Brooklyn Dodgers). [1]
- Al Couture knockouts Ralph Walton in Lewiston Maine in 10.5 seconds. [1]
- Los Angeles (previously Cleveland) Rams play first NFL game in Los Angeles, California. [1]
- October 1
- First National League playoffs, Brooklyn Dodgers versus Saint Louis Cardinals (Saint Louis wins two games to 0). [1]
- Bob Feller is 348th strikeout of the season. [1]
- October 15
- Enos Slaughter scores a run from first base on a single in the 43rd World Series. [1]
- Saint Louis Cardinals beat Boston Red Sox, 4 games to 3 in 43rd World Series. [1]
- October 20
- Frank Seno returns kickoff 105 yards, Chicago Cardinals versus New York Giants. [1]
- November 1
- New York Knicks first basketball game, beating Toronto Huskies 68-66. [1]
- November 11
- New York Knicks' first game at Madison Square Garden loses 78-68 to Chicago Stags. [1]
- December 1
- Australia compiles 645 versus India at the Gabba (Donald Bradman 187). [1]
- December 3
- 12th Heisman Trophy Award: Glenn Davis, Army (Half Back). [1]
- December 15
- Chicago Bears beat New York Giants 24-14 in NFL championship game. [1]
- New York Giants' Frank Filchock and Merle Hapes are suspended by NFL, because they didn't report bribe attempt. [1]
- December 17
- Donald Bradman and Barnes complete 405 run 5th wicket stand, score 234 each. [1]
- December 22
- Cleveland Browns beat New York Yankees 14-9 in AAFC championship game. [1]
- December 23
- University of Tennessee refuses to play Duquesne University, because they may use a black player in their basketball game. [1]
- December 26
- 35th Davis Cup: USA beats Australia in Melbourne (5-0). [1]
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