- April 18
- "The Great One" Wayne Gretzky plays his final National Hockey League game. [20]
- May 1
- 125th Kentucky Derby: Chris Antley aboard Charismatic wins in 2:03.2. [1]
- May 7
- The Cleveland Indians score 18 runs in the final three innings to overcome a 9-1 deficit to beat the Tampa Bay Devil Rays, 20-11. [56]
- May 8
- Jimmy Glass scores the goal that keeps Carlisle United in the Football League. [20]
- May 15
- 125th Preakness: Chris Antley on Charismatic wins in 1:55.2. [1]
- May 23
- Canadian professional wrestler Owen Hart dies after falling 90 feet as he was being lowered into the ring for the "Over the Edge" sports entertainment event in Kansas City, Missouri. [20] [467]
- May 26
- Manchester United wins the UEFA Champions League at the Nou Camp stadium, Barcelona, beating Bayern Munich to lift their third major trophy of the season, after winning the English Premier League and FA Cup, an unprecedented feat for a single season. [20]
- June 16
- Sociedade Esportiva Palmeiras wins the Libertadores Cup. [20]
- June 19
- The Dallas Stars defeat the Buffalo Sabres in triple overtime of game six of the Stanley Cup Finals to win their first Stanley Cup. Brett Hull scores the controversial cup-winning goal to seal the victory. [20]
- June 25
- The San Antonio Spurs defeat the New York Knicks 78-77 in Game 5 of the NBA Finals to take home the title in a strike-shortened season. [20]
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- June 30
- After a loss at Wimbledon, Boris Becker announces that he will end his tennis career. [37]
- July 7
- In Rome, Hicham El Guerrouj runs the fastest mile ever recorded - 3:43:13. [20]
- July 18
- David Cone pitches a perfect game, the 16th in history, as the New York Yankees defeat the Montreal Expos, 6-0, to celebrate Yogi Berra Day. [20]
- July 25
- Lance Armstrong wins his first Tour de France (cycling). [20]
- August 13
- Steffi Graf announces her retirement from tennis after a 17 year career in which she won 107 career titles including 22 Grand Slams. [20]
- August 17
- Baltimore Orioles' pitcher Jesse Orosco sets a major league mark pitching in his 1,072nd game. [56]
- August 26
- Michael Johnson captures the 400m world record. [20]
- September 11
- Eric Milton of the Minnesota Twins pitches a 7-0 no-hitter against the Anaheim Angels. [20]
- October 27
- The New York Yankees complete a four-game sweep of the Atlanta Braves to win their second consecutive World Series of baseball. [20] [56]
- November 2
- The National Basketball Association launches NBA.com TV, a 24-hour TV network. [457]
- November 22
- Wayne Gretzky is inducted into the Hockey Hall of Fame, his number 99 permanently retired by the National Hockey League. [20]
- November 28
- The Hamilton Tiger-Cats defeat the Calgary Stampeders 32-21 to win the 87th Grey Cup at B.C. Place Stadium in Vancouver. [20]
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